A hereditary autosomal dominant corneal dystrophy that is characterized by the development of small granules on the stromal layer of the cornea which later develop into lesions with a lattice-like appearance. The lesions increase in size with age and may lead to decreased visual acuity. Mutations in the TGFBI gene have been identified.
Type:
Amyloidosis
ICD-10 Classification
Diseases of the Eye and Adnexa
Tissue:
Eye
Precursor Proteins:
×
Protein Information
Primary Name:
Transforming growth factor-beta-induced protein ig-h3
