AmyCo

Basic Information

Disease Name:

Castleman Disease

Alternative Names:

Angiofollicular Lymph Hyperplasia
Angiofollicular Lymph Node Hyperplasia
Angiofollicular Lymphoid Hyperplasia
Castleman's Disease
Castleman's Tumor
Castlemans Disease
Giant Lymph Node Hyperplasia
Hyperplasia, Giant Lymph Node
Lymph Node Hyperplasia, Giant

MeSH Description:

Large benign, hyperplastic lymph nodes. The more common hyaline vascular subtype is characterized by small hyaline vascular follicles and interfollicular capillary proliferations. Plasma cells are often present and represent another subtype with the plasma cells containing IgM and immunoglobulin A.

Type:

Clinical condition associated with amyloidosis

ICD-10 Classification

Neoplasms

Tissue:

Liver, Lymph Node, Spleen, Kidney, Thyroid Gland, Heart

Associated Amyloidosis:

AA Amyloidosis

Precursor Proteins:

Primary Name:	Serum amyloid A-1 protein
Gene Name:	SAA1
Alternative Protein Names:	Serum amyloid A-1 protein (SAA) [Cleaved into: Amyloid protein A (Amyloid fibril protein AA); Serum amyloid protein A(2-104); Serum amyloid protein A(3-104); Serum amyloid protein A(2-103); Serum amyloid protein A(2-102); Serum amyloid protein A(4-101)]
ISA Nomenclature:	AA
Protein Length:	122
Precursor Protein Sequence:	MKLLTGLVFCSLVLGVSSRSFFSFLGEAFDGARDMWRAYSDMREANYIGSDKYFHARGNYDAAKRGPGGVWAAEAISDARENIQRFFGHGAEDSLADQAANEWGRSGKDPNHFRPAGLPEKY
UniProt AC:	P0DJI8
UniProt ID:	SAA1_HUMAN
AmyPro:	AP00005

Primary Name:	Serum amyloid A-2 protein
Gene Name:	SAA2
Alternative Protein Names:	Serum amyloid A-2 protein (SAA2)
ISA Nomenclature:	AA
Protein Length:	122
Precursor Protein Sequence:	MKLLTGLVFCSLVLSVSSRSFFSFLGEAFDGARDMWRAYSDMREANYIGSDKYFHARGNYDAAKRGPGGAWAAEVISNARENIQRLTGRGAEDSLADQAANKWGRSGRDPNHFRPAGLPEKY
UniProt AC:	P0DJI9
UniProt ID:	SAA2_HUMAN
AmyPro:

Co-deposited Proteins:

No information available

MeSH:
ICD:
OMIM:
PubMed:

Protein Information

Protein Information