ID: 34

Disease Name: Lewy Body Disease

Description: A neurodegenerative disease characterized by dementia, mild parkinsonism, and fluctuations in attention and alertness. The neuropsychiatric manifestations tend to precede the onset of bradykinesia, muscle rigidity, and other extrapyramidal signs. Delusions and visual hallucinations are relatively frequent in this condition. Histologic examination reveals lewy bodies in the cerebral cortex and brain stem. Senile plaques and other pathologic features characteristic of Alzheimer disease may also be present.

Disease Type: Amyloidosis

ICD-10 Classification: Diseases of the Nervous System

Tissue: Central Nervous System (CNS)

Cross References
http://apps.who.int/classifications/icd10/browse/2016/en#/G31

http://apps.who.int/classifications/icd10/browse/2016/en#/F02

https://meshb.nlm.nih.gov/record/ui?ui=D020961

https://www.omim.org/entry/127750

https://www.ncbi.nlm.nih.gov/pubmed/2683563

https://www.ncbi.nlm.nih.gov/pubmed/1436523

Alternative Names:
Cortical Lewy Body Disease
Dementia, Lewy Body
Diffuse Lewy Body Disease
Lewy Body Dementia
Lewy Body Disease, Cortical
Lewy Body Disease, Diffuse
Lewy Body Type Senile Dementia

Precursor Proteins:
P05067 | Amyloid-beta A4 protein
P37840 | Alpha-synuclein


Co-deposited Proteins:
No information available



Link to Amyloidosis: 
	No information available
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