ID: 38

Disease Name: Lattice corneal dystrophy type 1

Description: A hereditary autosomal dominant form of corneal dystrophy with significant phenotypic variability. It is characterized by polymorphic geographic deposits at Bowman's membrane, lattice corneal dystrophy, recurrent corneal ulceration, and mild progressive visual impairment. Mutations in the TGBFI gene have been identified.

Disease Type: Amyloidosis

ICD-10 Classification: Diseases of the Eye and Adnexa

Tissue: Eye

Cross References
http://apps.who.int/classifications/icd10/browse/2016/en#/H18

https://meshb.nlm.nih.gov/record/ui?ui=C537881

https://www.omim.org/entry/122200

https://www.ncbi.nlm.nih.gov/pubmed/9657906

https://www.ncbi.nlm.nih.gov/pubmed/13814113

Alternative Names:
Biber-Haab-Dimmer Dystrophy
Corneal Dystrophy, Lattice Type I
Corneal dystrophy, lattice type 1
Lattice Corneal Dystrophy Type I
Lattice Corneal Dystrophy, Type I
Classic lattice corneal dystrophy
LCD1
LCDI 
LCD
CDL1

Precursor Proteins:
Q15582 | Transforming growth factor-beta-induced protein ig-h3


Co-deposited Proteins:
P02649 | Apolipoprotein E
P10909 | Clusterin


Link to Amyloidosis: 
	No information available
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