ID: 39

Disease Name: Insomnia, Fatal Familial

Description: An autosomal dominant disorder characterized by degeneration of the thalamus and progressive insomnia. It is caused by a mutation in the prion protein (prions).

Disease Type: Amyloidosis

ICD-10 Classification: Certain Infectious and Parasitic Diseases

Tissue: Central Nervous System (CNS)

Cross References
http://apps.who.int/classifications/icd10/browse/2016/en#/A81

https://meshb.nlm.nih.gov/record/ui?ui=D034062

https://www.omim.org/entry/600072

https://www.ncbi.nlm.nih.gov/pubmed/3762620

https://www.ncbi.nlm.nih.gov/pubmed/1346338

https://www.ncbi.nlm.nih.gov/pubmed/7654073

https://www.ncbi.nlm.nih.gov/pubmed/28324299

Alternative Names:
Familial Fatal Insomnia
Insomnia Familial Fatal
Fatal Familial Disease 

Precursor Proteins:
P04156 | Major prion protein


Co-deposited Proteins:
No information available



Link to Amyloidosis: 
	No information available
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