{
    "name": "Spondylitis, Ankylosing",
    "descriptions": "A chronic inflammatory condition affecting the axial joints, such as the sacroiliac joint and other intervertebral or costovertebral joints. It occurs predominantly in young males and is characterized by pain and stiffness of joints (ankylosis) with inflammation at tendon insertions.",
    "type": "Clinical conditions associated with amyloidosis",
    "association": "Diseases of the Musculoskeletal System and Connective Tissue",
    "tissue": "Kidney, Liver, Adrenal Gland",
    "proteins": [
        {
            "name": "Serum amyloid A-1 protein",
            "ac": "P0DJI8",
            "id": "SAA1_HUMAN",
            "seq": "MKLLTGLVFCSLVLGVSSRSFFSFLGEAFDGARDMWRAYSDMREANYIGSDKYFHARGNYDAAKRGPGGVWAAEAISDARENIQRFFGHGAEDSLADQAANEWGRSGKDPNHFRPAGLPEKY",
            "length": 122,
            "genename": "SAA1",
            "type": "Precursor Protein"
        },
        {
            "name": "Serum amyloid A-2 protein",
            "ac": "P0DJI9",
            "id": "SAA2_HUMAN",
            "seq": "MKLLTGLVFCSLVLSVSSRSFFSFLGEAFDGARDMWRAYSDMREANYIGSDKYFHARGNYDAAKRGPGGAWAAEVISNARENIQRLTGRGAEDSLADQAANKWGRSGRDPNHFRPAGLPEKY",
            "length": 122,
            "genename": "SAA2",
            "type": "Precursor Protein"
        }
    ],
    "alternative_names": [
        "Ankylosing Spondylarthritis",
        "Ankylosing Spondylitis",
        "Ankylosing Spondyloarthritis",
        "Bechterew Disease",
        "Bechterew's Disease",
        "Marie-Struempell Disease",
        "Rheumatoid Spondylitis",
        "Spondylarthritis Ankylopoietica",
        "Spondylitis Ankylopoietica",
        "Spondyloarthritis Ankylopoietica"
    ],
    "crossreferences": [
        {
            "abbreviation": "ICD",
            "link": "http://apps.who.int/classifications/icd10/browse/2016/en#/M45"
        },
        {
            "abbreviation": "MeSH",
            "link": "https://meshb.nlm.nih.gov/record/ui?ui=D013167"
        },
        {
            "abbreviation": "PubMed",
            "link": "https://www.ncbi.nlm.nih.gov/pubmed/13498599"
        },
        {
            "abbreviation": "PubMed",
            "link": "https://www.ncbi.nlm.nih.gov/pubmed/7022798"
        },
        {
            "abbreviation": "PubMed",
            "link": "https://www.ncbi.nlm.nih.gov/pubmed/23283540"
        }
    ],
    "mappings_amyloid": [
        "http://83.212.109.111:8084/amyco/29"
    ],
    "isa_name": ""
}