ID: 62

Disease Name: Cystic Fibrosis

Description: An autosomal recessive genetic disease of the exocrine glands. It is caused by mutations in the gene encoding the cystic fibrosis transmembrane conductance regulator expressed in several organs including the lung, the pancreas, the biliary system, and the sweat glands. Cystic fibrosis is characterized by epithelial secretory dysfunction associated with ductal obstruction resulting in airway obstruction; chronic respiratory infections; pancreatic insufficiency; maldigestion; salt depletion; and heat prostration.

Disease Type: Clinical conditions associated with amyloidosis

ICD-10 Classification: Endocrine, Nutritional and Metabolic Diseases

Tissue: Kidney, Liver, Spleen, Heart, Gastrointestinal Tract, Lung

Cross References
http://apps.who.int/classifications/icd10/browse/2016/en#/E84

https://meshb.nlm.nih.gov/record/ui?ui=D003550

https://www.ncbi.nlm.nih.gov/pubmed/7246499

https://www.ncbi.nlm.nih.gov/pubmed/888804

https://www.ncbi.nlm.nih.gov/pubmed/3953498

https://www.ncbi.nlm.nih.gov/pubmed/3925758

https://www.ncbi.nlm.nih.gov/pubmed/25054230

Alternative Names:
Cystic Fibrosis of Pancreas
Fibrocystic Disease of Pancreas
Mucoviscidosis
Pancreatic Cystic Fibrosis
Pulmonary Cystic Fibrosis

Precursor Proteins:
P0DJI8 | Serum amyloid A-1 protein
P0DJI9 | Serum amyloid A-2 protein


Co-deposited Proteins:
No information available



Link to Amyloidosis: 
	http://83.212.109.111:8084/amyco/29

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