ID: 65

Disease Name: Periodic fever, familial, autosomal dominant

Description: An inherited condition characterized by recurrent episodes of fever; onset is typically in early childhood. Fevers usually persist for about three weeks, though they can be longer or shorter, and may not occur again for several weeks or several years. Other symptoms may include abdominal pain; myalgia; arthralgia; skin rash and systemic inflammation; amyloidosis may also occur in some cases. There is often no trigger, but episodes are sometimes preceded by infections, injury, or stress. Germline mutations in the TNFRSFIA gene have been identified.

Disease Type: Clinical conditions associated with amyloidosis

ICD-10 Classification: Diseases of the Musculoskeletal System and Connective Tissue

Tissue: Kidney

Cross References
https://www.ncbi.nlm.nih.gov/pubmed/23965844

https://www.ncbi.nlm.nih.gov/pubmed/11239851

https://www.ncbi.nlm.nih.gov/pubmed/11443543

https://meshb.nlm.nih.gov/record/ui?ui=C536657

https://www.omim.org/entry/142680

Alternative Names:
Autosomal Dominant Familial Periodic Fever
Familial Hibernian fever
Hibernian Familial Fever
Hibernian fever, familial
TNF Receptor-associated Periodic Syndrome
Tumor necrosis factor receptor-associated periodic syndrome
TRAPS
TRAPS syndrome
Tumor necrosis factor receptor 1 associated periodic syndrome
TNF receptor 1-associated periodic syndrome
FPF
FHF

Precursor Proteins:
P0DJI8 | Serum amyloid A-1 protein
P0DJI9 | Serum amyloid A-2 protein


Co-deposited Proteins:
No information available



Link to Amyloidosis: 
	http://83.212.109.111:8084/amyco/29

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