ID: 69

Disease Name: Sjogren's Syndrome

Description: Chronic inflammatory and autoimmune disease in which the salivary and lacrimal glands undergo progressive destruction by lymphocytes and plasma cells resulting in decreased production of saliva and tears. The primary form, often called sicca syndrome, involves both keratoconjunctivitis sicca and xerostomia. The secondary form includes, in addition, the presence of a connective tissue disease, usually rheumatoid arthritis.

Disease Type: Clinical conditions associated with amyloidosis

ICD-10 Classification: Diseases of the Musculoskeletal System and Connective Tissue

Tissue: Lung, Skin, Kidney, Salivary Gland, Soft Tissues, Lachrymal Gland

Cross References
https://www.ncbi.nlm.nih.gov/pubmed/4682027

https://www.ncbi.nlm.nih.gov/pubmed/30210893

https://www.ncbi.nlm.nih.gov/pubmed/28202864

https://www.ncbi.nlm.nih.gov/pubmed/29787840

https://www.ncbi.nlm.nih.gov/pubmed/26339445

http://apps.who.int/classifications/icd10/browse/2016/en#/M35

https://meshb.nlm.nih.gov/record/ui?ui=D012859

https://www.omim.org/entry/270150

Alternative Names:
Sicca Syndrome
Sjogren Syndrome
SS

Precursor Proteins:
P02766 | Transthyretin
P0DOX7 | Immunoglobulin kappa light chain
P0DOX8 | Immunoglobulin lambda-1 light chain


Co-deposited Proteins:
No information available



Link to Amyloidosis: 
	http://83.212.109.111:8084/amyco/8
	http://83.212.109.111:8084/amyco/30
	http://83.212.109.111:8084/amyco/42

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