ID: 70

Disease Name: Lupus Erythematosus, Systemic

Description: A chronic, relapsing, inflammatory, and often febrile multisystemic disorder of connective tissue, characterized principally by involvement of the skin, joints, kidneys, and serosal membranes. It is of unknown etiology, but is thought to represent a failure of the regulatory mechanisms of the autoimmune system. The disease is marked by a wide range of system dysfunctions, an elevated erythrocyte sedimentation rate, and the formation of LE cells in the blood or bone marrow.

Disease Type: Clinical conditions associated with amyloidosis

ICD-10 Classification: Diseases of the Musculoskeletal System and Connective Tissue

Tissue: Kidney, Heart, Lung, Bone Marrow, Gastrointestinal Tract, Liver, Spleen, Adrenal Cortex

Cross References
https://www.ncbi.nlm.nih.gov/pubmed/991472

https://www.ncbi.nlm.nih.gov/pubmed/17687556

https://www.ncbi.nlm.nih.gov/pubmed/13381422

https://www.ncbi.nlm.nih.gov/pubmed/20477021

http://apps.who.int/classifications/icd10/browse/2016/en#/M32

https://meshb.nlm.nih.gov/record/ui?ui=D008180

https://www.omim.org/entry/152700

Alternative Names:
Libman-Sacks Disease
Lupus Erythematosus Disseminatus
Systemic Lupus Erythematosus
SLE

Precursor Proteins:
P0DJI8 | Serum amyloid A-1 protein
P0DJI9 | Serum amyloid A-2 protein


Co-deposited Proteins:
No information available



Link to Amyloidosis: 
	http://83.212.109.111:8084/amyco/29

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