ID: 74

Disease Name: Pick Disease of the Brain

Description: A rare form of dementia that is sometimes familial. Clinical features include aphasia; apraxia; confusion; anomia; memory loss; and personality deterioration. This pattern is consistent with the pathologic findings of circumscribed atrophy of the poles of the frontal lobe and temporal lobe. Neuronal loss is maximal in the hippocampus, entorhinal cortex, and amygdala. Some ballooned cortical neurons contain argentophylic (Pick) bodies.

Disease Type: Amyloidosis

ICD-10 Classification: Diseases of the Nervous System

Tissue: Central Nervous System (CNS)

Cross References
http://apps.who.int/classifications/icd10/browse/2016/en#/G31

https://meshb.nlm.nih.gov/record/ui?ui=D020774

https://www.omim.org/entry/172700

https://www.ncbi.nlm.nih.gov/pubmed/30158706

Alternative Names:
Brain Atrophy, Circumscribed Lobar
Circumscribed Lobar Atrophy of the Brain
Dementia with Lobar Atrophy and Neuronal Cytoplasmic Inclusions
Lobar Atrophy (Brain)
Lobar Atrophy Of Brain
Lobar Atrophy of the Brain
Pick Disease
Pick Disease Of Brain
Pick's Disease
Picks Disease of Brain

Precursor Proteins:
P10636 | Tau


Co-deposited Proteins:
No information available



Link to Amyloidosis: 
	No information available
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